PRESENTATIONS
authorized documents
Welcome by Conference organizers
Sylvio BENGIO, Adebiotech / Christophe DINI, Oroxcell
Session 1 – INNOVATIONS: New Alternative Methods (NAMs) and new approaches to reduce animal testing
Apical out lung organoids as a relevant tool to study respiratory diseases
Thibault HONEGGER, NETRI
Brain–on–chip devices/ integration of different technologies into the same chip
Sinan KARABOGA / Stéphane GÉGOUT, HARMONIC PHARMA
QSAR assisted Predictive toxicology and animal experimentation replacement
Yuri DANCIK, CERTARA (USA / UK)
In vitro–in vivo extrapolation of dermal absorption of topically applied drug products using physiologically based pharmacokinetic (PBPK) modeling
Nicolas VIOLLE, ETAP–LAB
Reducing animal use in efficacy studies of complex neurological diseases: good and bad news
Gregory LEMKINE, WATCHFROG LABORATORIES
New Alternative Methods (NAMs) for endocrine disruptors testing lessons learnt from applying OECD guidelines
Sébastien RENOUF, PathoQuest
RNA Next–Generation Sequencing transcriptomics analysis: an alternative validated method to replace animal in vivo tests for assessing the viral safety of cell based Biologics
FLASH CORPORATE PRESENTATIONS
Altertox, Valentin SALAMONE
CTIBiotech, Nico FORRAZ
Episkin, Christelle VIDEAU
Epithelix, Samuel CONSTANT
Fluigent, Aurélie MORYTKO
Harmonic Pharma, Aurélien STAB
MatTek, Miroslav KANĎÁR
NETRI, Thibault HONEGGER
Oroxcell, Christophe DINI
PerkinElmer/Revvity, Julian BURSZTYKA
SABEU, Karina CUANALO–CONTRERAS
Vibiosphen, Patricia MARTIN
Session 2 – Pharmaceutical industry applications
Yunhai CUI, BOEHRINGER INGELHEIM GmbH (Germany)
EpiIntestinal microtissues as a model for Firstpass drug metabolism and transport
Jan–Lund OTTESEN, Novo Nordisk (Denmark)
A future without laboratory animals – what does it take?
Samuel CONSTANT, EPITHELIX
Models in infectiology and respiratory diseases: OECD validation, safety and efficacy
Session 3 – Chemical industries, medical devices and Cosmetics
Thomas LÉOPOLD, FRANCE CHIMIE
Review of the evolution of REACH requirements and role of the NAM (new alternative methods)
Peter CORNELIS, NELSON LABS (Belgium)
The Biocompatrail: a challenging hike towards animal–free testing of Medical Devices
Colin MC GUCKIN, CTIBiotech
Bioimpedance–connected and vascularized 3D bioprinted human skin chip for high throughput efficacy testing
FLASH SCIENTIFICS POSTERS
Éric ANDRES, Oroxcell
Skin sensitization and photosensitization evaluation through LC–MS/MS, HRMS and 3D reconstructed tissue approaches : An integrative evaluation strategy addressing the mixtures challenge
Mendy BOUVERET, Epithelix
Novel fully primary human airway epithelium–alveolar macrophages in vitro co–cultures models to study host pathogen interactions
Karina CUANALO–CONTRERAS, SABEU
Membrane technology for tissue engineering
Alan DUBOIS, GIS FC3R
Mapping of Replacement in France based on the projects submitted for the second call for projects of the FC3R
Edith FILAIRE, ICARE Laboratoire / Pierre GAUDRIAULT, Cherry Biotech
Innovative in vitro 3D skin model for safety assessment: a case report for the skin sensitization
Christina LE TANNO, UMR1011 – Récepteurs Nucléaires – Maladies Métaboliques et Cardiovasculaires
Microfluidic pump systems: a way to replace animal models to study aortic endothelial cells response and viability to high shear stress
Astrid CAPELLO, Galapagos
Assessing compounds using an animal–free testing strategy
Nicolas GAUDENZIO, Genoskin
The HyposkinⓇ platform: a unique framework to decipher the early steps of human immune response to vaccines at the site of injection
Elodie OLIVIER, Laboratoire de Chimie–Toxicologie Analytique et Cellulaire, Faculté de Pharmacie, Université Paris Cité
Hormonal impact of bisphenols A, F and S in human placental cells
Benoit CUDENNEC, UMRT BioEcoAgro 1158 Univ. Lille
In vitro and in vivo comparison of the DPP–IV inhibitory activity of dietary proteins from different origins after gastrointestinal digestion
Elodie VANDENHAUTE, HCS Pharma
Bridging the gap between in vitro & in vivo: 3D cell culture considering the extracellular matrix
Session 4 – Nutrition
Jonna KOPER, LESAFFRE
Intestinal simulators in the 3R context
Anthony TREIZEBRE, LILLE UNIVERSITY
Organs–on–Chips: a new technological revolution for Food Safety and health impact
Noëmie DANIEL, SYMRISE
Complementary animal and advanced in vitro models to investigate the role of polyphenols and gut microbiota–host relationship in metabolic diseases
GENERAL TRANSDISCIPLINARY ROUND TABLE and CONFERENCE CONCLUSIONS
